DNA Sequencing

We were studying DNA Sequencing and learned about how to read part of a DNA sequencing gel, you go from the botom of the gel, up, reading each separate band in the order that they occur. Each band is under a certain letter, and then you write the letter it's under. We practiced this by reading the sequencing gels of 3 different patients, and comparing them to someone named Norm's gel. Norm has the DNA sequence of an average person, so we found the percentage of each person's sequencing that was the same as Norm's. People who are to far off, have a good chance of disease, as compared to people who are very similar to Norm.

Norm was used as the control in this experiment. All of the people in the above graph were compared to Norm. Norm himself wasn't on the graph but the numbers shown for each person shows the percentage of their DNA Sequencing that is the same as Norms.  In order to find the percentage similar, we took the the number of DNA that was the same and divided it by the total DNA, then multiplied that number by 100 to get the percentage. We grouped the the DNA into groups of 3. They're were 33 different bases making 11 groups. Each group could then be used to determine a protein sequence.  There is a good chance that Carol has a disease because of the genetic flaw. Bob and  Abby however are similar to Bob, and have a better chance of living without a disease. Abby had the closest Protein sequence, then Bob, and then Carol had the worst compared to Norm.